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Genomic organization of human transcription initiation complexesΒΆ

droso Genomic organization of human transcription initiation complexes Bryan J. Venters, and B. Franklin Pugh Nature 2013 Sep 18. doi: 10.1038/nature12535

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Dear Colleague

We wanted to bring to your attention a paper that is being retracted. When the matter was brought to our attention, it soon became clear that we incorrectly performed certain analyses in the paper, which lead to conclusions that were no longer valid. We then undertook a new study to determine if the main conclusions could be substantiated by re-analysis of the data. The main conclusions as they relate to CPEs could not be substantiated. To the best of our knowledge the raw and processed human TFIIB, TBP, and Pol II ChIP-exo data are valid, but subject to standard false discovery considerations.

Kind regards,
Frank Pugh and Bryan Venters